Regenerative Properties of Recombinant Human Erythropoietin in the Wound Healing

BACKGROUND: Erythropoietin (EPO) is the main stimulator of erythropoiesis, but EPO also has non-hematopoietic effects. The recent data show positive effects on tissue regeneration. AIM: This review aims to know highlights pathophysiological mechanisms at different stages regeneration, and possible clinical applications in wound healing. METHODS: A literature considering reviews, studies, original papers, articles from electronic been used. RESULTS: Analysis animal studies several trials using context healing revealed that a effect all regeneration process may be promising therapeutic strategy for treatment chronic wounds. CONCLUSION: An improved understanding functions regulatory lead new considerations this growth hormone its regular application patients.